Trimethylation of Elongation Factor-Tu by the Dual Thermoregulated Methyltransferase EftM Does Not Impact Its Canonical Function in Translation

The Pseudomonas aeruginosa methyltransferase EftM trimethylates elongation factor-Tu (EF-Tu) on lysine 5 to form a post-translational modification important for initial bacterial adherence to host epithelial cells. EftM methyltransferase activity is directly temperature regulated. The protein stabil...

Descripción completa

Detalles Bibliográficos
Autores principales: Prezioso, Samantha M., Duong, Duc M., Kuiper, Emily G., Deng, Qiudong, Albertí, Sebastián, Conn, Graeme L., Goldberg, Joanna B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401129/
https://www.ncbi.nlm.nih.gov/pubmed/30837495
http://dx.doi.org/10.1038/s41598-019-39331-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401129/
https://www.ncbi.nlm.nih.gov/pubmed/30837495
http://dx.doi.org/10.1038/s41598-019-39331-x

Ejemplares similares