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DESTINI: A deep-learning approach to contact-driven protein structure prediction

The amino acid sequence of a protein encodes the blueprint of its native structure. To predict the corresponding structural fold from the protein’s sequence is one of most challenging problems in computational biology. In this work, we introduce DESTINI (deep structural inference for proteins), a no...

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Detalles Bibliográficos
Autores principales: Gao, Mu, Zhou, Hongyi, Skolnick, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401133/
https://www.ncbi.nlm.nih.gov/pubmed/30837676
http://dx.doi.org/10.1038/s41598-019-40314-1