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Subtle changes in chromatin loop contact propensity are associated with differential gene regulation and expression
While genetic variation at chromatin loops is relevant for human disease, the relationships between contact propensity (the probability that loci at loops physically interact), genetics, and gene regulation are unclear. We quantitatively interrogate these relationships by comparing Hi-C and molecula...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401380/ https://www.ncbi.nlm.nih.gov/pubmed/30837461 http://dx.doi.org/10.1038/s41467-019-08940-5 |