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The Immunogenicity of OMP31 Peptides and Its Protection Against Brucella melitensis Infection in Mice

Given brucellosis is a widespread zoonosis in the world, a safe and effective vaccine is urgently needed. Recent trend in vaccine design has shifted to epitope-based vaccines that are safe and specific. In this study, peptide containing both T-cell and B-cell epitopes of OMP31 was synthesized and us...

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Detalles Bibliográficos
Autores principales: Zhang, Fengbo, Li, Zhiwei, Jia, Bin, Zhu, Yuejie, Pang, Pan, Zhang, Chuntao, Ding, Jianbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401381/
https://www.ncbi.nlm.nih.gov/pubmed/30837598
http://dx.doi.org/10.1038/s41598-019-40084-w