Structural Basis of Nanobodies Targeting the Prototype Norovirus

Human norovirus infections are a major disease burden. In this study, we analyzed three new norovirus-specific Nanobodies that interacted with the prototype human norovirus (i.e., genogroup I genotype 1 [GI.1]). We showed that the Nanobodies bound on the side (Nano-7 and Nano-62) and top (Nano-94) o...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruoff, Kerstin, Kilic, Turgay, Devant, Jessica, Koromyslova, Anna, Ringel, Alessa, Hempelmann, Alexander, Geiss, Celina, Graf, Juliane, Haas, Michelle, Roggenbach, Imme, Hansman, Grant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Structure and Assembly
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401464/
https://www.ncbi.nlm.nih.gov/pubmed/30602609
http://dx.doi.org/10.1128/JVI.02005-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401464/
https://www.ncbi.nlm.nih.gov/pubmed/30602609
http://dx.doi.org/10.1128/JVI.02005-18

Ejemplares similares