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Structural Basis of Nanobodies Targeting the Prototype Norovirus

Human norovirus infections are a major disease burden. In this study, we analyzed three new norovirus-specific Nanobodies that interacted with the prototype human norovirus (i.e., genogroup I genotype 1 [GI.1]). We showed that the Nanobodies bound on the side (Nano-7 and Nano-62) and top (Nano-94) o...

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Detalles Bibliográficos
Autores principales:	Ruoff, Kerstin, Kilic, Turgay, Devant, Jessica, Koromyslova, Anna, Ringel, Alessa, Hempelmann, Alexander, Geiss, Celina, Graf, Juliane, Haas, Michelle, Roggenbach, Imme, Hansman, Grant
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Structure and Assembly
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401464/ https://www.ncbi.nlm.nih.gov/pubmed/30602609 http://dx.doi.org/10.1128/JVI.02005-18

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