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The ESCRT-Related ATPase Vps4 Is Modulated by Interferon during Herpes Simplex Virus 1 Infection

Interferons (IFNs) and autophagy are critical neuronal defenses against viral infection. IFNs alter neuronal autophagy by promoting the accumulation of IFN-dependent LC3-decorated autophagic structures, termed LC3 clusters. Here, we analyzed LC3 clusters in sensory ganglia following herpes simplex v...

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Detalles Bibliográficos
Autores principales: Cabrera, Jorge Ruben, Manivanh, Richard, North, Brian J., Leib, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401484/
https://www.ncbi.nlm.nih.gov/pubmed/30837340
http://dx.doi.org/10.1128/mBio.02567-18