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Therapeutic effects of human monoclonal PSMA antibody-mediated TRIM24 siRNA delivery in PSMA-positive castration-resistant prostate cancer

Background and Aims: Prostate specific membrane antigen (PSMA) is specifically expressed on prostate epithelial cells and markedly overexpressed in almost all prostate cancers. TRIM24 is also up-regulated from localized prostate cancer to metastatic castration-resistant prostate cancer (CRPC). Becau...

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Detalles Bibliográficos
Autores principales: Shi, Sheng-Jia, Wang, Li-Juan, Han, Dong-Hui, Wu, Jie-Heng, Jiao, Dian, Zhang, Kai-Liang, Chen, Jiang-Wei, Li, Yu, Yang, Fa, Zhang, Jing-Liang, Zheng, Guo-Xu, Yang, An-Gang, Zhao, Ai-Zhi, Qin, Wei-Jun, Wen, Wei-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401511/
https://www.ncbi.nlm.nih.gov/pubmed/30867828
http://dx.doi.org/10.7150/thno.29884