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Therapeutic effects of human monoclonal PSMA antibody-mediated TRIM24 siRNA delivery in PSMA-positive castration-resistant prostate cancer
Background and Aims: Prostate specific membrane antigen (PSMA) is specifically expressed on prostate epithelial cells and markedly overexpressed in almost all prostate cancers. TRIM24 is also up-regulated from localized prostate cancer to metastatic castration-resistant prostate cancer (CRPC). Becau...
Autores principales: | Shi, Sheng-Jia, Wang, Li-Juan, Han, Dong-Hui, Wu, Jie-Heng, Jiao, Dian, Zhang, Kai-Liang, Chen, Jiang-Wei, Li, Yu, Yang, Fa, Zhang, Jing-Liang, Zheng, Guo-Xu, Yang, An-Gang, Zhao, Ai-Zhi, Qin, Wei-Jun, Wen, Wei-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401511/ https://www.ncbi.nlm.nih.gov/pubmed/30867828 http://dx.doi.org/10.7150/thno.29884 |
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