Immune Checkpoint B7x (B7-H4/B7S1/VTCN1) is Over Expressed in Spontaneous Canine Bladder Cancer: The First Report and its Implications in a Preclinical Model

BACKGROUND: B7x (B7-H4/B7S1/VTCN1), an inhibitory immune checkpoint molecule is a potential therapeutic target owing to its immunosuppressive effect and well-known expression in cancers. Immune checkpoints in canine bladder cancer are largely undefined. Here, we report the first evaluation on expres...

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Detalles Bibliográficos
Autores principales: Chand, Damini, Dhawan, Deepika, Sankin, Alexander, Ren, Xiaoxin, Lin, Juan, Schoenberg, Mark, Knapp, Deborah W., Zang, Xingxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2019
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401562/
https://www.ncbi.nlm.nih.gov/pubmed/30854414
http://dx.doi.org/10.3233/BLC-180204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401562/
https://www.ncbi.nlm.nih.gov/pubmed/30854414
http://dx.doi.org/10.3233/BLC-180204

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