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Immune Checkpoint B7x (B7-H4/B7S1/VTCN1) is Over Expressed in Spontaneous Canine Bladder Cancer: The First Report and its Implications in a Preclinical Model
BACKGROUND: B7x (B7-H4/B7S1/VTCN1), an inhibitory immune checkpoint molecule is a potential therapeutic target owing to its immunosuppressive effect and well-known expression in cancers. Immune checkpoints in canine bladder cancer are largely undefined. Here, we report the first evaluation on expres...
Autores principales: | Chand, Damini, Dhawan, Deepika, Sankin, Alexander, Ren, Xiaoxin, Lin, Juan, Schoenberg, Mark, Knapp, Deborah W., Zang, Xingxing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401562/ https://www.ncbi.nlm.nih.gov/pubmed/30854414 http://dx.doi.org/10.3233/BLC-180204 |
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