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The Potential Role of the NLRP3 Inflammasome Activation as a Link Between Mitochondria ROS Generation and Neuroinflammation in Postoperative Cognitive Dysfunction

Postoperative cognitive dysfunction (POCD) is commonly observed in perioperative care following major surgery and general anesthesia in elderly individuals. No preventive or interventional agents have been established so far. Although the role of interleukin-1β (IL-1β)-mediated neuroinflammation fol...

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Detalles Bibliográficos
Autores principales: Wei, Penghui, Yang, Fan, Zheng, Qiang, Tang, Wenxi, Li, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401615/
https://www.ncbi.nlm.nih.gov/pubmed/30873011
http://dx.doi.org/10.3389/fncel.2019.00073