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Proteasome Dependent Actin Remodeling Facilitates Antigen Extraction at the Immune Synapse of B Cells

Engagement of the B cell receptor (BCR) with surface-tethered antigens leads to the formation of an immune synapse (IS), where cell signaling and antigen uptake are tightly coordinated. Centrosome re-orientation to the immune synapse has emerged as a critical regulatory step to guide the local recru...

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Detalles Bibliográficos
Autores principales: Ibañez-Vega, Jorge, Del Valle Batalla, Felipe, Saez, Juan José, Soza, Andrea, Yuseff, Maria-Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401660/
https://www.ncbi.nlm.nih.gov/pubmed/30873155
http://dx.doi.org/10.3389/fimmu.2019.00225