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Polyelectrolyte Complexation of Oligonucleotides by Charged Hydrophobic—Neutral Hydrophilic Block Copolymers

Polyelectrolyte complex micelles (PCMs, core-shell nanoparticles formed by complexation of a polyelectrolyte with a polyelectrolyte-hydrophilic neutral block copolymer) offer a solution to the critical problem of delivering therapeutic nucleic acids, Despite this, few systematic studies have been co...

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Detalles Bibliográficos
Autores principales: Marras, Alexander E., Vieregg, Jeffrey R., Ting, Jeffrey M., Rubien, Jack D., Tirrell, Matthew V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402004/
https://www.ncbi.nlm.nih.gov/pubmed/30960067
http://dx.doi.org/10.3390/polym11010083