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Association of genetically predicted testosterone with thromboembolism, heart failure, and myocardial infarction: mendelian randomisation study in UK Biobank

OBJECTIVE: To determine whether endogenous testosterone has a causal role in thromboembolism, heart failure, and myocardial infarction. DESIGN: Two sample mendelian randomisation study using genetic variants as instrumental variables, randomly allocated at conception, to infer causality as additiona...

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Detalles Bibliográficos
Autores principales: Luo, Shan, Au Yeung, Shiu Lun, Zhao, Jie V, Burgess, Stephen, Schooling, C Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402044/
https://www.ncbi.nlm.nih.gov/pubmed/30842065
http://dx.doi.org/10.1136/bmj.l476