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Importance of finding the bona fide target of the Fanconi anemia pathway

Fanconi anemia (FA) is a rare genetic disease characterized by the deficiency of the cellular response and repair pathway for DNA interstrand crosslink (ICL) damage. Although recent studies have revealed the detailed molecular functions of FA proteins encoded by 22 genes, the mechanism of occurrence...

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Detalles Bibliográficos
Autores principales: Sakai, Wataru, Sugasawa, Kaoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402094/
https://www.ncbi.nlm.nih.gov/pubmed/30873250
http://dx.doi.org/10.1186/s41021-019-0122-y