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Herd immunity alters the conditions for performing dose schedule comparisons: an individual-based model of pneumococcal carriage

BACKGROUND: There is great interest in the use of reduced dosing schedules for pneumococcal conjugate vaccines, a strategy premised on maintaining an acceptable level of protection against disease and carriage of the organism. We asked about the practicality of measuring differential effectiveness a...

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Detalles Bibliográficos
Autores principales: Yang, Alan, Cai, Francisco, Lipsitch, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402138/
https://www.ncbi.nlm.nih.gov/pubmed/30836941
http://dx.doi.org/10.1186/s12879-019-3833-6