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Single‐Dose and Multiple‐Dose Pharmacokinetics of Vaniprevir in Healthy Men

Vaniprevir is an inhibitor of the hepatitis C virus (HCV) NS3/4A protease. The aim of these double‐blind, placebo‐controlled phase I studies was to evaluate the safety and pharmacokinetics of vaniprevir in healthy male volunteers. The primary objective for both studies was the safety and tolerabilit...

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Detalles Bibliográficos
Autores principales: Caro, L, de Hoon, J, Depré, M, Cilissen, C, Miller, J, Gao, W, Panebianco, D, Guo, Z, Troemel, SL, Anderson, MS, Uemura, N, Butterton, J, Wagner, J, Wright, DH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402189/
https://www.ncbi.nlm.nih.gov/pubmed/28796416
http://dx.doi.org/10.1111/cts.12482