Key Amino Acid Substitution for Infection-Enhancing Activity-Free Designer Dengue Vaccines

Dengue is a globally important disease caused by four serotypes of dengue virus. Dengue vaccine development has been hampered by antigenic cross-reactivity among serotypes, which potentially causes antibody-dependent enhancement of infection and disease severity. Here we found that a single amino ac...

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Detalles Bibliográficos
Autores principales: Yamanaka, Atsushi, Konishi, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402262/
https://www.ncbi.nlm.nih.gov/pubmed/30826727
http://dx.doi.org/10.1016/j.isci.2019.02.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402262/
https://www.ncbi.nlm.nih.gov/pubmed/30826727
http://dx.doi.org/10.1016/j.isci.2019.02.012

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