Improvement of quantitative structure–activity relationship (QSAR) tools for predicting Ames mutagenicity: outcomes of the Ames/QSAR International Challenge Project

The International Conference on Harmonization (ICH) M7 guideline allows the use of in silico approaches for predicting Ames mutagenicity for the initial assessment of impurities in pharmaceuticals. This is the first international guideline that addresses the use of quantitative structure–activity re...

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Detalles Bibliográficos
Autores principales: Honma, Masamitsu, Kitazawa, Airi, Cayley, Alex, Williams, Richard V, Barber, Chris, Hanser, Thierry, Saiakhov, Roustem, Chakravarti, Suman, Myatt, Glenn J, Cross, Kevin P, Benfenati, Emilio, Raitano, Giuseppa, Mekenyan, Ovanes, Petkov, Petko, Bossa, Cecilia, Benigni, Romualdo, Battistelli, Chiara Laura, Giuliani, Alessandro, Tcheremenskaia, Olga, DeMeo, Christine, Norinder, Ulf, Koga, Hiromi, Jose, Ciloy, Jeliazkova, Nina, Kochev, Nikolay, Paskaleva, Vesselina, Yang, Chihae, Daga, Pankaj R, Clark, Robert D, Rathman, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Manuscript
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402315/
https://www.ncbi.nlm.nih.gov/pubmed/30357358
http://dx.doi.org/10.1093/mutage/gey031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402315/
https://www.ncbi.nlm.nih.gov/pubmed/30357358
http://dx.doi.org/10.1093/mutage/gey031

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