TRIM69 inhibits cataractogenesis by negatively regulating p53

Ultraviolet B (UVB) irradiation can induce reactive oxygen species (ROS) production and apoptosis in human lens epithelial cells (HLECs), thus leading to the formation of cataracts. We studied the role of tripartite motif 69 (TRIM69) in cataract formation. The expression of TRIM69 protein was down-r...

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Detalles Bibliográficos
Autores principales: Rong, Xianfang, Rao, Jun, Li, Dan, Jing, Qinghe, Lu, Yi, Ji, Yinghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402377/
https://www.ncbi.nlm.nih.gov/pubmed/30844644
http://dx.doi.org/10.1016/j.redox.2019.101157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402377/
https://www.ncbi.nlm.nih.gov/pubmed/30844644
http://dx.doi.org/10.1016/j.redox.2019.101157

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