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TRIM69 inhibits cataractogenesis by negatively regulating p53
Ultraviolet B (UVB) irradiation can induce reactive oxygen species (ROS) production and apoptosis in human lens epithelial cells (HLECs), thus leading to the formation of cataracts. We studied the role of tripartite motif 69 (TRIM69) in cataract formation. The expression of TRIM69 protein was down-r...
Autores principales: | Rong, Xianfang, Rao, Jun, Li, Dan, Jing, Qinghe, Lu, Yi, Ji, Yinghong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402377/ https://www.ncbi.nlm.nih.gov/pubmed/30844644 http://dx.doi.org/10.1016/j.redox.2019.101157 |
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