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Atrophy in midbrain & cerebral/cerebellar pedunculi is characteristic for progressive supranuclear palsy – A double-validation whole-brain meta-analysis

OBJECTIVE: Progressive supranuclear palsy (PSP) is an atypical parkinsonian syndrome characterized by vertical gaze palsy and postural instability. Midbrain atrophy is suggested as a hallmark, but it has not been validated systematically in whole-brain imaging. METHODS: We conducted whole-brain meta...

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Detalles Bibliográficos
Autores principales: Albrecht, Franziska, Bisenius, Sandrine, Neumann, Jane, Whitwell, Jennifer, Schroeter, Matthias L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402426/
https://www.ncbi.nlm.nih.gov/pubmed/30831462
http://dx.doi.org/10.1016/j.nicl.2019.101722