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Genetic ablation of TAZ induces HepG2 liver cancer cell apoptosis through activating the CaMKII/MIEF1 signaling pathway

BACKGROUND AND OBJECTIVE: Transcriptional coactivator with PDZ-binding motif (TAZ) has been found to be associated with tumor progression. Mitochondrial homeostasis regulates cancer cell viability and metastasis. However, the roles of TAZ and mitochondrial homeostasis in liver cancer viability have...

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Detalles Bibliográficos
Autores principales: Hou, Yi, Lan, Chunna, Kong, Ying, Zhu, Chunjiao, Peng, Wenna, Huang, Zhichao, Zhang, Changjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402445/
https://www.ncbi.nlm.nih.gov/pubmed/30881030
http://dx.doi.org/10.2147/OTT.S196142