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Activation of the epithelial sodium channel (ENaC) leads to cytokine profile shift to pro‐inflammatory in labor

The shift of cytokine profile from anti‐ to pro‐inflammatory is the most recognizable sign of labor, although the underlying mechanism remains elusive. Here, we report that the epithelial sodium channel (ENaC) is upregulated and activated in the uterus at labor in mice. Mechanical activation of ENaC...

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Detalles Bibliográficos
Autores principales: Sun, Xiao, Guo, Jing Hui, Zhang, Dan, Chen, Jun‐jiang, Lin, Wei Yin, Huang, Yun, Chen, Hui, Huang, Wen Qing, Liu, Yifeng, Tsang, Lai Ling, Yu, Mei Kuen, Chung, Yiu Wa, Jiang, Xiaohua, Huang, Hefeng, Chan, Hsiao Chang, Ruan, Ye Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402451/
https://www.ncbi.nlm.nih.gov/pubmed/30154237
http://dx.doi.org/10.15252/emmm.201808868