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Implications of the HDAC6-ERK1 feed-forward loop in immunotherapy

The oncogene HDAC6 controls numerous cell processes that are related to tumorigenesis and metastasis, and has recently arisen as a target to treat malignancies. The ERK cascade is a classic pathway driving oncogenesis, and the components of this pathway are either highly mutated in cancers or are vi...

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Detalles Bibliográficos
Autores principales: Wu, Jheng-Yu, Moses, Niko, Bai, Wenlong, Zhang, Xiaohong Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402502/
https://www.ncbi.nlm.nih.gov/pubmed/30854521
http://dx.doi.org/10.29245/2578-3009/2018/3.1143