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Implications of the HDAC6-ERK1 feed-forward loop in immunotherapy
The oncogene HDAC6 controls numerous cell processes that are related to tumorigenesis and metastasis, and has recently arisen as a target to treat malignancies. The ERK cascade is a classic pathway driving oncogenesis, and the components of this pathway are either highly mutated in cancers or are vi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402502/ https://www.ncbi.nlm.nih.gov/pubmed/30854521 http://dx.doi.org/10.29245/2578-3009/2018/3.1143 |