DR region specific antibody ameliorated but ouabain worsened renal injury in nephrectomized rats through regulating Na,K-ATPase mediated signaling pathways

Reduced Na(+)-K(+)-ATPase function is reported in various renal diseases. This implies that increase of Na(+)-K(+)-ATPase function may be a new target in treatment of renal injury. We previously reported that Na(+)-K(+)-ATPase was stabilized by DRm217, a specific antibody against DR region of Na(+)-...

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Detalles Bibliográficos
Autores principales: Wang, Juan, Ullah, Sayyed Hanif, Li, Meihe, Zhang, Miao, Zhang, Fujun, Zheng, Jin, Yan, Xiaofei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402514/
https://www.ncbi.nlm.nih.gov/pubmed/30807290
http://dx.doi.org/10.18632/aging.101815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402514/
https://www.ncbi.nlm.nih.gov/pubmed/30807290
http://dx.doi.org/10.18632/aging.101815

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