Pleiotropic effect of common PHOX2B variants in Hirschsprung disease and neuroblastoma

Hirschsprung disease (HSCR) is a heterogeneous congenital disorder that affects the enteric nervous system, while neuroblastoma is an embryonal tumor of the sympathetic nervous system. Familial cases of both HSCR and neuroblastoma appear to be functionally linked to PHOX2B, which plays a key role in...

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Detalles Bibliográficos
Autores principales: Zhao, Jinglu, Zhu, Yun, Xie, Xiaoli, Yao, Yuxiao, Zhang, Jiao, Zhang, Ruizhong, Huang, Lihua, Cheng, Jiwen, Xia, Huimin, He, Jing, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402522/
https://www.ncbi.nlm.nih.gov/pubmed/30799307
http://dx.doi.org/10.18632/aging.101834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402522/
https://www.ncbi.nlm.nih.gov/pubmed/30799307
http://dx.doi.org/10.18632/aging.101834

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