Cargando…

Pleiotropic effect of common PHOX2B variants in Hirschsprung disease and neuroblastoma

Hirschsprung disease (HSCR) is a heterogeneous congenital disorder that affects the enteric nervous system, while neuroblastoma is an embryonal tumor of the sympathetic nervous system. Familial cases of both HSCR and neuroblastoma appear to be functionally linked to PHOX2B, which plays a key role in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Jinglu, Zhu, Yun, Xie, Xiaoli, Yao, Yuxiao, Zhang, Jiao, Zhang, Ruizhong, Huang, Lihua, Cheng, Jiwen, Xia, Huimin, He, Jing, Zhang, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402522/ https://www.ncbi.nlm.nih.gov/pubmed/30799307 http://dx.doi.org/10.18632/aging.101834

Ejemplares similares

Association of VAMP5 and MCC genetic polymorphisms with increased risk of Hirschsprung disease susceptibility in Southern Chinese children
por: Zhao, Jinglu, et al.
Publicado: (2018)

Associations of SLC6A20 genetic polymorphisms with Hirschsprung’s disease in a Southern Chinese population
por: Xie, Xiaoli, et al.
Publicado: (2019)

Associations between common genetic variants in microRNAs and Hirschsprung disease susceptibility in Southern Chinese children
por: Wu, Qi, et al.
Publicado: (2021)

Contributions of PHOX2B in the Pathogenesis of Hirschsprung Disease
por: Fernández, Raquel María, et al.
Publicado: (2013)

Association of Common Genetic Variants in Pre-microRNAs and Neuroblastoma Susceptibility: A Two-Center Study in Chinese Children
por: He, Jing, et al.
Publicado: (2018)

Association of NRG1 and AUTS2 genetic polymorphisms with Hirschsprung disease in a South Chinese population
por: Zhang, Yan, et al.
Publicado: (2018)

Association between DSCAM polymorphisms and non-syndromic Hirschsprung disease in Chinese population
por: Wang, Yong, et al.
Publicado: (2018)

RET and PHOX2B Genetic Polymorphisms and Hirschsprung's Disease Susceptibility: A Meta-Analysis
por: Liang, Chun-mei, et al.
Publicado: (2014)

Common variations within HACE1 gene and neuroblastoma susceptibility in a Southern Chinese population
por: Zhang, Zhuorong, et al.
Publicado: (2017)

Large-scale replication study identified multiple independent SNPs in RET synergistically associated with Hirschsprung disease in Southern Chinese population
por: Zhang, Yan, et al.
Publicado: (2017)

Association of potentially functional variants in the XPG gene with neuroblastoma risk in a Chinese population
por: He, Jing, et al.
Publicado: (2016)

Association between ABHD1 and DOK6 polymorphisms and susceptibility to Hirschsprung disease in Southern Chinese children
por: Lan, Chaoting, et al.
Publicado: (2021)

KRAS rs7973450 A>G increases neuroblastoma risk in Chinese children: a four-center case-control study
por: Lin, Ao, et al.
Publicado: (2019)

PHOX2B is a suppressor of neuroblastoma metastasis
por: Naftali, Osnat, et al.
Publicado: (2016)

Associations between lncRNA MEG3 polymorphisms and neuroblastoma risk in Chinese children
por: Zhuo, Zhen-Jian, et al.
Publicado: (2018)

LMO1 super-enhancer polymorphism rs2168101 G>T correlates with decreased neuroblastoma risk in Chinese children
por: He, Jing, et al.
Publicado: (2018)

LINC00673 rs11655237 C>T confers neuroblastoma susceptibility in Chinese population
por: Zhang, Zhuorong, et al.
Publicado: (2018)

Functional Polymorphisms at ERCC1/XPF Genes Confer Neuroblastoma Risk in Chinese Children
por: Zhuo, Zhen-Jian, et al.
Publicado: (2018)

Lack of Associations between XPC Gene Polymorphisms and Neuroblastoma Susceptibility in a Chinese Population
por: Zheng, Jintao, et al.
Publicado: (2016)

Comprehensive Analysis of NRG1 Common and Rare Variants in Hirschsprung Patients
por: Luzón-Toro, Berta, et al.
Publicado: (2012)

Potentially functional polymorphisms in the LIN28B gene contribute to neuroblastoma susceptibility in Chinese children
por: He, Jing, et al.
Publicado: (2016)

The TP53 gene rs1042522 C>G polymorphism and neuroblastoma risk in Chinese children
por: He, Jing, et al.
Publicado: (2017)

PHOX2A and PHOX2B are differentially regulated during retinoic acid-driven differentiation of SK-N-BE(2)C neuroblastoma cell line
por: Di Lascio, Simona, et al.
Publicado: (2016)

Epistatic Association of CD14 and NOTCH2 Genetic Polymorphisms with Biliary Atresia in a Southern Chinese Population
por: Lin, Zefeng, et al.
Publicado: (2018)

Association between NEFL Gene Polymorphisms and Neuroblastoma Risk in Chinese Children: A Two-Center Case-Control Study
por: Wu, Qiang, et al.
Publicado: (2018)

Genetic Variations of GWAS-Identified Genes and Neuroblastoma Susceptibility: a Replication Study in Southern Chinese Children()()()
por: He, Jing, et al.
Publicado: (2017)

Two novel mutations in exon 3 of PHOX2B gene: think about congenital central hypoventilation syndrome in patients with Hirschsprung disease
por: Paglietti, Maria Giovanna, et al.
Publicado: (2019)

A respiratory/Hirschsprung phenotype in a three‐generation family associated with a novel pathogenic PHOX2B splice donor mutation
por: Pace, Nikolai Paul, et al.
Publicado: (2020)

The Association between GWAS-identified BARD1 Gene SNPs and Neuroblastoma Susceptibility in a Southern Chinese Population
por: Zhang, Ruizhong, et al.
Publicado: (2016)

Super-enhancer-associated TTC8 alters the nucleocytoplasmic distribution of PHOX2B and activates MAPK signaling in neuroblastoma
por: Zhuo, Ran, et al.
Publicado: (2022)

LMO1 gene polymorphisms contribute to decreased neuroblastoma susceptibility in a Southern Chinese population
por: He, Jing, et al.
Publicado: (2016)

Distinct Neuroblastoma-associated Alterations of PHOX2B Impair Sympathetic Neuronal Differentiation in Zebrafish Models
por: Pei, Desheng, et al.
Publicado: (2013)

Targeting of PHOX2B expression allows the identification of drugs effective in counteracting neuroblastoma cell growth
por: Zanni, Eleonora Di, et al.
Publicado: (2017)

The interplay of common genetic variants NRG1 rs2439302 and RET rs2435357 increases the risk of developing Hirschsprung’s disease
por: Chi, Shuiqing, et al.
Publicado: (2023)

HSD17B12 gene rs11037575 C>T polymorphism confers neuroblastoma susceptibility in a Southern Chinese population
por: Zhang, Zhuorong, et al.
Publicado: (2017)

Establishment and identification of an animal model of Hirschsprung disease in suckling mice
por: Lan, Chaoting, et al.
Publicado: (2023)

Associated congenital heart disease with Hirschsprung's disease: a retrospective cohort study on 2,174 children
por: Wu, Yujian, et al.
Publicado: (2023)

YTHDF1 gene polymorphisms and neuroblastoma susceptibility in Chinese children: an eight-center case-control study
por: Liu, Jiabin, et al.
Publicado: (2021)

HMGA2 Gene rs8756 A>C Polymorphism Reduces Neuroblastoma Risk in Chinese Children: A Four-Center Case-Control Study
por: Liu, Jiabin, et al.
Publicado: (2020)

PDGFA gene rs9690350 polymorphism increases biliary atresia risk in Chinese children
por: Liu, Fei, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_h45m0u9s397ea0hs5pgg69k8bi