Pathological priming causes developmental gene network heterochronicity in autism patient-derived neurons

Autism spectrum disorder (ASD) is thought to emerge during early cortical development. However, the exact developmental stages and associated molecular networks that prime disease propensity are elusive. To profile early neurodevelopmental alterations in ASD with macrocephaly, we monitored patient-d...

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Detalles Bibliográficos
Autores principales: Schafer, Simon T., Paquola, Apua C.M., Stern, Shani, Gosselin, David, Ku, Manching, Pena, Monique, Kuret, Thomas J.M., Liyanage, Marvin, Mansour, Abed AlFatah, Jaeger, Baptiste N., Marchetto, Maria C., Glass, Christopher K., Mertens, Jerome, Gage, Fred H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402576/
https://www.ncbi.nlm.nih.gov/pubmed/30617258
http://dx.doi.org/10.1038/s41593-018-0295-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402576/
https://www.ncbi.nlm.nih.gov/pubmed/30617258
http://dx.doi.org/10.1038/s41593-018-0295-x

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