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Pathological priming causes developmental gene network heterochronicity in autism patient-derived neurons
Autism spectrum disorder (ASD) is thought to emerge during early cortical development. However, the exact developmental stages and associated molecular networks that prime disease propensity are elusive. To profile early neurodevelopmental alterations in ASD with macrocephaly, we monitored patient-d...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402576/ https://www.ncbi.nlm.nih.gov/pubmed/30617258 http://dx.doi.org/10.1038/s41593-018-0295-x |