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Induced aneuploidy in neural stem cells triggers a delayed stress response and impairs adult life span in flies
Studying aneuploidy during organism development has strong limitations because chronic mitotic perturbations used to generate aneuploidy usually result in lethality. We developed a genetic tool to induce aneuploidy in an acute and time-controlled manner during Drosophila development. This is achieve...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402706/ https://www.ncbi.nlm.nih.gov/pubmed/30794535 http://dx.doi.org/10.1371/journal.pbio.3000016 |