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Global gene expression of histologically normal primary skin cells from BCNS subjects reveals “single-hit” effects that are influenced by rapamycin

Studies of dominantly heritable cancers enabled insights about tumor progression. BCNS is a dominantly inherited disorder that is characterized by developmental abnormalities and postnatal neoplasms, principally BCCs. We performed an exploratory gene expression profiling of primary cell cultures der...

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Detalles Bibliográficos
Autores principales: Phatak, Amruta, Athar, Mohammad, Crowell, James A., Leffel, David, Herbert, Brittney-Shea, Bale, Allen E., Kopelovich, Levy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402716/
https://www.ncbi.nlm.nih.gov/pubmed/30858923
http://dx.doi.org/10.18632/oncotarget.26640