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State transitions in the substantia nigra reticulata predict the onset of motor deficits in models of progressive dopamine depletion in mice
Parkinson’s disease (PD) is a progressive neurodegenerative disorder whose cardinal motor symptoms are attributed to dysfunction of basal ganglia circuits under conditions of low dopamine. Despite well-established physiological criteria to define basal ganglia dysfunction, correlations between indiv...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402832/ https://www.ncbi.nlm.nih.gov/pubmed/30839276 http://dx.doi.org/10.7554/eLife.42746 |