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Attenuated chromatin compartmentalization in meiosis and its maturation in sperm development
Germ cells manifest a unique gene expression program and regain totipotency in the zygote. Here, we perform Hi-C analysis to examine 3D chromatin organization in male germ cells during spermatogenesis. We show that the highly compartmentalized 3D chromatin organization characteristic of interphase n...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402993/ https://www.ncbi.nlm.nih.gov/pubmed/30778237 http://dx.doi.org/10.1038/s41594-019-0189-y |