Cargando…

Attenuated chromatin compartmentalization in meiosis and its maturation in sperm development

Germ cells manifest a unique gene expression program and regain totipotency in the zygote. Here, we perform Hi-C analysis to examine 3D chromatin organization in male germ cells during spermatogenesis. We show that the highly compartmentalized 3D chromatin organization characteristic of interphase n...

Descripción completa

Detalles Bibliográficos
Autores principales: Alavattam, Kris G., Maezawa, So, Sakashita, Akihiko, Khoury, Haia, Barski, Artem, Kaplan, Noam, Namekawa, Satoshi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402993/
https://www.ncbi.nlm.nih.gov/pubmed/30778237
http://dx.doi.org/10.1038/s41594-019-0189-y