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Attenuated chromatin compartmentalization in meiosis and its maturation in sperm development

Germ cells manifest a unique gene expression program and regain totipotency in the zygote. Here, we perform Hi-C analysis to examine 3D chromatin organization in male germ cells during spermatogenesis. We show that the highly compartmentalized 3D chromatin organization characteristic of interphase n...

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Detalles Bibliográficos
Autores principales: Alavattam, Kris G., Maezawa, So, Sakashita, Akihiko, Khoury, Haia, Barski, Artem, Kaplan, Noam, Namekawa, Satoshi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402993/
https://www.ncbi.nlm.nih.gov/pubmed/30778237
http://dx.doi.org/10.1038/s41594-019-0189-y

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