Immunoglobulin deposition on biomolecule corona determines complement opsonisation efficiency of preclinical and clinical nanoparticles

Deposition of complement factors (opsonisation) on nanoparticles may promote clearance from the blood by macrophages and trigger proinflammatory responses, but the mechanisms regulating the efficiency of complement activation are poorly understood. We previously demonstrated that opsonisation of sup...

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Detalles Bibliográficos
Autores principales: Vu, Vivian P., Gifford, Geoffrey B., Chen, Fangfang, Benasutti, Halli, Wang, Guankui, Groman, Ernest V., Scheinman, Robert, Saba, Laura, Moghimi, Seyed Moein, Simberg, Dmitri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402998/
https://www.ncbi.nlm.nih.gov/pubmed/30643271
http://dx.doi.org/10.1038/s41565-018-0344-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402998/
https://www.ncbi.nlm.nih.gov/pubmed/30643271
http://dx.doi.org/10.1038/s41565-018-0344-3

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