Efficient editing DNA regions with high sequence identity in actinomycetal genomes by a CRISPR-Cas9 system

Actinobacteria able to produce varieties of bioactive natural products have been long appreciated by the field of drug discovery and development. Recently, a few of CRISPR/Cas9 systems bearing different types of replicons (pSG5 and pIJ101) were developed to efficiently edit their genomes. Despite wi...

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Detalles Bibliográficos
Autores principales: Mo, Jingjun, Wang, Shuwen, Zhang, Wan, Li, Chunyu, Deng, Zixin, Zhang, Lixin, Qu, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403111/
https://www.ncbi.nlm.nih.gov/pubmed/30891508
http://dx.doi.org/10.1016/j.synbio.2019.02.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403111/
https://www.ncbi.nlm.nih.gov/pubmed/30891508
http://dx.doi.org/10.1016/j.synbio.2019.02.004

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