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Melatonin Therapy Modulates Cerebral Metabolism and Enhances Remyelination by Increasing PDK4 in a Mouse Model of Multiple Sclerosis

Metabolic disturbances have been implicated in demyelinating diseases including multiple sclerosis (MS). Melatonin, a naturally occurring hormone, has emerged as a potent neuroprotective candidate to reduce myelin loss and improve MS outcomes. In this study, we evaluated the effect of melatonin, at...

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Detalles Bibliográficos
Autores principales: Ghareghani, Majid, Scavo, Linda, Jand, Yahya, Farhadi, Naser, Sadeghi, Hossein, Ghanbari, Amir, Mondello, Stefania, Arnoult, Damien, Gharaghani, Sajjad, Zibara, Kazem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403148/
https://www.ncbi.nlm.nih.gov/pubmed/30873027
http://dx.doi.org/10.3389/fphar.2019.00147