Emergence of Microglia Bearing Senescence Markers During Paralysis Progression in a Rat Model of Inherited ALS

Age is a recognized risk factor for amyotrophic lateral sclerosis (ALS), a paralytic disease characterized by progressive loss of motor neurons and neuroinflammation. A hallmark of aging is the accumulation of senescent cells. Yet, the pathogenic role of cellular senescence in ALS remains poorly und...

Descripción completa

Detalles Bibliográficos
Autores principales: Trias, Emiliano, Beilby, Pamela R., Kovacs, Mariángeles, Ibarburu, Sofía, Varela, Valentina, Barreto-Núñez, Romina, Bradford, Samuel C., Beckman, Joseph S., Barbeito, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403180/
https://www.ncbi.nlm.nih.gov/pubmed/30873018
http://dx.doi.org/10.3389/fnagi.2019.00042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403180/
https://www.ncbi.nlm.nih.gov/pubmed/30873018
http://dx.doi.org/10.3389/fnagi.2019.00042

Ejemplares similares