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Emergence of Microglia Bearing Senescence Markers During Paralysis Progression in a Rat Model of Inherited ALS

Age is a recognized risk factor for amyotrophic lateral sclerosis (ALS), a paralytic disease characterized by progressive loss of motor neurons and neuroinflammation. A hallmark of aging is the accumulation of senescent cells. Yet, the pathogenic role of cellular senescence in ALS remains poorly und...

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Detalles Bibliográficos
Autores principales:	Trias, Emiliano, Beilby, Pamela R., Kovacs, Mariángeles, Ibarburu, Sofía, Varela, Valentina, Barreto-Núñez, Romina, Bradford, Samuel C., Beckman, Joseph S., Barbeito, Luis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403180/ https://www.ncbi.nlm.nih.gov/pubmed/30873018 http://dx.doi.org/10.3389/fnagi.2019.00042

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