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Mechanism of Regulation of Big-Conductance Ca(2+)-Activated K(+) Channels by mTOR Complex 2 in Podocytes

Podocytes, dynamic polarized cells wrapped around glomerular capillaries, are an essential component of the glomerular filtration barrier. BK channels consist of one of the slit diaphragm (SD) proteins in podocytes, interact with the actin cytoskeleton, and play vital roles in glomerular filtration....

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Detalles Bibliográficos
Autores principales: Wang, Yinhang, Tao, Jie, Wang, Mengling, Yang, Licai, Ning, Fengling, Xin, Hong, Xu, Xudong, Cai, Hui, Zhang, Weiguang, Yu, Ker, Zhang, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403181/
https://www.ncbi.nlm.nih.gov/pubmed/30873046
http://dx.doi.org/10.3389/fphys.2019.00167