Species-Specific Structural Requirements of Alpha-Branched Trehalose Diester Mincle Agonists

Despite the ever present need for an effective Mycobacterium tuberculosis (Mtb) vaccine, efforts for development have been largely unsuccessful. Correlates of immune protection against Mtb are not wholly defined, but Th1 and likely Th17 adaptive immune responses have been demonstrated to be necessar...

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Detalles Bibliográficos
Autores principales: Smith, Alyson J., Miller, Shannon M., Buhl, Cassandra, Child, Robert, Whitacre, Margaret, Schoener, Roman, Ettenger, George, Burkhart, David, Ryter, Kendal, Evans, Jay T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403188/
https://www.ncbi.nlm.nih.gov/pubmed/30873180
http://dx.doi.org/10.3389/fimmu.2019.00338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403188/
https://www.ncbi.nlm.nih.gov/pubmed/30873180
http://dx.doi.org/10.3389/fimmu.2019.00338

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