Tryptophan hydroxylase (TRH) loss of function mutations in Daphnia deregulated growth, energetic, serotoninergic and arachidonic acid metabolic signalling pathways

Serotonin has a pivotal function regulating development, growth, reproduction and behavior in animals. In this paper, we studied the deregulatory effects of the deprivation of serotonin in Daphnia magna TRH CRISPR-Cas9 mutants. Bi-allelic in-del THR mutants and, to a lesser extent, mono-allelic ones...

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Detalles Bibliográficos
Autores principales: Campos, Bruno, Rivetti, Claudia, Tauler, Roma, Piña, Benjamin, Barata, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403212/
https://www.ncbi.nlm.nih.gov/pubmed/30842467
http://dx.doi.org/10.1038/s41598-019-39987-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403212/
https://www.ncbi.nlm.nih.gov/pubmed/30842467
http://dx.doi.org/10.1038/s41598-019-39987-5

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