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Proteomic changes in oocytes after in vitro maturation in lipotoxic conditions are different from those in cumulus cells
Maternal lipolytic metabolic disorders result in a lipotoxic microenvironment in the ovarian follicular fluid (FF) which deteriorates oocyte quality. Although cellular stress response mechanisms are well defined in somatic cells, they remain largely unexplored in oocytes, which have distinct organel...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403224/ https://www.ncbi.nlm.nih.gov/pubmed/30842615 http://dx.doi.org/10.1038/s41598-019-40122-7 |