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Proteomic changes in oocytes after in vitro maturation in lipotoxic conditions are different from those in cumulus cells

Maternal lipolytic metabolic disorders result in a lipotoxic microenvironment in the ovarian follicular fluid (FF) which deteriorates oocyte quality. Although cellular stress response mechanisms are well defined in somatic cells, they remain largely unexplored in oocytes, which have distinct organel...

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Detalles Bibliográficos
Autores principales: Marei, Waleed F. A., Van Raemdonck, Geert, Baggerman, Geert, Bols, Peter E. J., Leroy, Jo L. M. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403224/
https://www.ncbi.nlm.nih.gov/pubmed/30842615
http://dx.doi.org/10.1038/s41598-019-40122-7