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Methodological refinement of Aldara-induced psoriasiform dermatitis model in mice

Imiquimod (IMQ)-induced skin inflammation is currently the most widely accepted psoriasis animal model, however, it features several limitations. We have modified the IMQ-model to minimize its systemic effects towards effectively maintaining the characteristic skin reactions. The original protocol (...

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Detalles Bibliográficos
Autores principales: Horváth, Szabina, Komlódi, Rita, Perkecz, Anikó, Pintér, Erika, Gyulai, Rolland, Kemény, Ágnes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403245/
https://www.ncbi.nlm.nih.gov/pubmed/30842501
http://dx.doi.org/10.1038/s41598-019-39903-x