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Methodological refinement of Aldara-induced psoriasiform dermatitis model in mice
Imiquimod (IMQ)-induced skin inflammation is currently the most widely accepted psoriasis animal model, however, it features several limitations. We have modified the IMQ-model to minimize its systemic effects towards effectively maintaining the characteristic skin reactions. The original protocol (...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403245/ https://www.ncbi.nlm.nih.gov/pubmed/30842501 http://dx.doi.org/10.1038/s41598-019-39903-x |