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Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis

The balance between self-renewal and differentiation of hematopoietic stem and progenitor cells (HSPCs) maintains hematopoietic homeostasis, failure of which can lead to hematopoietic disorder. HSPC fate is controlled by signals from the bone marrow niche resulting in alteration of the stem cell tra...

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Detalles Bibliográficos
Autores principales: Kidoya, Hiroyasu, Muramatsu, Fumitaka, Shimamura, Teppei, Jia, Weizhen, Satoh, Takashi, Hayashi, Yumiko, Naito, Hisamichi, Kunisaki, Yuya, Arai, Fumio, Seki, Masahide, Suzuki, Yutaka, Osawa, Tsuyoshi, Akira, Shizuo, Takakura, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403248/
https://www.ncbi.nlm.nih.gov/pubmed/30842549
http://dx.doi.org/10.1038/s41467-019-09028-w