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ErbB3 Ligand Heregulin1 Is a Major Mitogenic Factor for Uncontrolled Lung Cancer Cell Proliferation()()

There are seven ligands for the epidermal growth factor receptor (EGFR) ErbB1 and two ligands for ErbB3. EGFR can form a homodimer or a heterodimer with ErbB3. In this study, we investigated whether homodimers or heterodimers, and which ligand, play a major role in cancer development, with the goal...

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Detalles Bibliográficos
Autores principales: Ma, Shiqi, Jia, Shijun, Ren, Yuan, Cao, Bangrong, Zha, Xiao, He, Jintao, Chen, Changmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403265/
https://www.ncbi.nlm.nih.gov/pubmed/30831376
http://dx.doi.org/10.1016/j.neo.2019.02.001