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The Transmembrane Conformation of the Influenza B Virus M2 Protein in Lipid Bilayers

Influenza A and B viruses cause seasonal flu epidemics. The M2 protein of influenza B (BM2) is a membrane-embedded tetrameric proton channel that is essential for the viral lifecycle. BM2 is a functional analog of AM2 but shares only 24% sequence identity for the transmembrane (TM) domain. The struc...

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Detalles Bibliográficos
Autores principales: Mandala, Venkata S., Liao, Shu-Yu, Gelenter, Martin D., Hong, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403292/
https://www.ncbi.nlm.nih.gov/pubmed/30842530
http://dx.doi.org/10.1038/s41598-019-40217-1